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Fig. 2 | Cancer Cell International

Fig. 2

From: CCNI2 promotes the progression of human gastric cancer through HDGF

Fig. 2

Knockdown of CCNI2 inhibits proliferation, promotes apoptosis and impedes migration of gastric cancer cells. A The proliferation of BGC-823 and SGC-7901 cells after knockdown of CCNI2 was measured using MTT assay. B Effects of altered CCNI2 expression on the ability of cell clone formation. C The effect of CCNI2 knockdown on apoptosis ability was determined by flow cytometry. D, E The migration of BGC-823 and SGC-7901 cells after knockdown of CCNI2 was measured using Transwell assay (D) and wound healing assay (E). shCCNI2 indicates CCNI2 knockdown in Gastric cancer cells; shCtrl indicates gastric cancer cells infected with a vector-expressing GFP. The presented results were representative of experiments repeated at least three times. Data was represented as mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001

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