Fig. 3

Knockdown of CCNI2 attenuates tumor formation of gastric cancer in vivo. A The total bioluminescent intensity was scanned using in vivo imaging system and used as a representation of tumor burden in mice. B Post injection of SGC-7901 cells, the tumor volume in mice was measured. (C, D) Mice were sacrificed at day 26 post injection, and the tumor weight was measured (C) and photographed (D). E The expression of Ki67 in mouse tumor tissues was detected by immunohistochemical staining. The presented results were representative of experiments repeated at least three times. Data was represented as mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001