Fig. 1From: PAR1 and PAR4 exert opposite effects on tumor growth and metastasis of esophageal squamous cell carcinoma via STAT3 and NF-κB signaling pathways The expression levels of PAR1 and PAR4 are inversely proportional in ESCC. A IHC detected the expression of PAR1 and PAR4 in ESCC tissues and paired para-carcinoma tissues and representative photomicrographs of immunohistochemical staining were shown in B. C Western blot and D RT-PCR detected the expression of PAR1 and PAR4 at protein level and mRNA level, respectively. E PAR1 and PAR4 mRNA expression data in ESCC patients were collected from TCGA database. F Western blot detected the expression of PAR1 and PAR4 in HEEC and ESCC cell lines (EC109, Kyse140, Kyse150 and TE-1). Data are presented as mean ± SD from three independent experiments; comparison between two groups, *P < 0.05; **P < 0.01; ***P < 0.001Back to article page