Fig. 5
Anti-tumor activity of PG in xenograft animal model. A BALB/c nude mice were inoculated subcutaneously with TFK-1 cells. When the tumor reached 100mm3, the nude mice (n = 5) were treated with DMSO or PG for 24 days. Representative images of tumor-bearing mice, B, C tumor weight and volume at different time points. D IHC staining was used to detect PCNA, Ki-67, LC3-II, and p62 proteins in tumor tissues of DMSO and PG groups. E H&E staining of vital organs in nude mice. Scale bar: 50 mm; *P < 0.05