Skip to main content
Fig. 1 | Cancer Cell International

Fig. 1

From: Identification and validation of cellular senescence patterns to predict clinical outcomes and immunotherapeutic responses in lung adenocarcinoma

Fig. 1

Cellular senescence-related molecular patterns with distinct prognosis and biological characteristics in LUAD. A Cophenetic correlation from NMF analysis of LUAD tumors. B Heatmap of the 74 cellular senescence-related prognostic genes in TCGA cohort. The age, gender, TNM stage, and survival status of TCGA LUAD cohorts were used as patient annotations. C Kaplan–Meier survival curves of LUAD patients in the three distinct clusters (P < 0.0001, Log-rank test). D GSVA enrichment analysis of Hallmark pathways in distinct cellular senescence clusters. Yellow indicated activated pathways, and blue indicated inhibited pathways. E The distribution of EMT scores in different cellular senescence clusters. The statistical difference of three gene clusters were compared through the Kruskal–Wallis test. (P < 0.001)

Back to article page

Cancer Cell International

ISSN: 1475-2867

Contact us