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Fig. 3 | Cancer Cell International

Fig. 3

From: Identification and validation of cellular senescence patterns to predict clinical outcomes and immunotherapeutic responses in lung adenocarcinoma

Fig. 3

Construction of cellular senescence score (CSS) and impact of CSS on clinical outcome for LUAD patients. A 336 cellular senescence clusters-related differentially expressed genes (DEGs) among three cellular senescence clusters were shown in the Venn diagram. B GO enrichment analysis of the 336 DEGs. C Kaplan–Meier curves for patients with high and low cellular senescence score. D Alluvial diagram showing the relations of cellular senescence clusters, cellular senescence score (CSS) and survival status of LUAD patients in TCGA cohort. E Comparison of cellular senescence score among three cellular senescence clusters. F The relative distributions of CCS between alive and dead patients in TCGA cohort. G Forrest plot of the univariate and multivariate Cox regression model analysis, which included factors of patients’ age, gender, TNM stage, and CSS in the TCGA cohort. ns not significant; *P < 0.05; **P < 0.01; ***P < 0.001

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