From: Intricate crosstalk between MYB and noncoding RNAs in cancer
Targeting MYB | Cellular processes | Tumor types | In vitro model | In vivo model | Refs. |
---|---|---|---|---|---|
miR-200 | Cell proliferation, resistance | Breast cancer | MCF-7, T47D cells | Â | [58] |
miR-143-3p | Cell proliferation, apoptosis | Breast cancer | Normal breast cell line MCF-10A, breast cancer cell line MDA-MB-435 | Â | [60] |
miR-195 | Cell proliferation, apoptosis, metastasis | NSCLC | A549, H129 | Female athymic nude mice | [100] |
miR-424 | Cell proliferation angiogenesis, metastasis | Ovarian cancer | The normal human ovarian epithelial cell line HOSEpiC, human ovarian cancer cell lines (SKOV-3, HO8910, A2780), HUVECs | Immunodeficient female nude mice | [121] |
miR-548c-3p | Cell proliferation, metastasis | Glioma | The human glioma T98G, U87, U251, HEK-293 cells (CRL-1573) | Â | [68] |
hsa-miR-495 | Cell proliferation, metastasis | Glioma | Human glioma cell lines (A172, U87, U251, U373) | Â | [69] |
miR-150 | Cell proliferation, apoptosis, cell cycle | Colorectal cancer, liver cancer, CML | K562, Meg-01, KCL-22, HL-60, KG-1; colorectal cancer cell line | Nude mice | |
miR-130a | Angiogenesis | GC | The human gastric cell line SGC7901, the human gastric mucosal epithelial cell line GES-1 | Female nude mice (BALB/C-nu, 6–8 weeks) | [118] |
miR-155 | Angiogenesis | GC | Human SGC-7901 cells, HEK293T cells, HUVEC cell | Male nude mice (BALB/C-nu) | [120] |
miR-29 | Cell cycle | Breast cancer | T-47D, MDA-MB-453, MCF-7, MCF-10A cells | Â | [61] |
miR-193b-3p | Cell proliferation | T-ALL | T-ALL cell lines | T-ALL patient samples | [67] |
miR-103a | Cell proliferation, metastasis | GC | MKN-45, HGC-27, MGC-803, SGC-7901, GES | Â | [30] |