Fig. 4
From: Attenuated expression of SNF5 facilitates progression of bladder cancer via STAT3 activation
SNF5 depletion promotes cell proliferation in vitro and in vivo. A CCK8 assay shows that reduced SNF5 facilitates the proliferation of both T24 and 5637 cells. B–C Colony formation assay was performed to evaluate cloning abilities SNF5-depleted or control BC cells. D–E Images of the xenograft tumors from nude mice with subcutaneously injected with SNF5-depleted or negative control BC cells. Tumor growth curves were plotted and tumor weights were compared in shNC group and shSNF5 group. F–G Immunohistochemistry assay of SNF5, Ki67 and Cleaved Caspase 3 expressions in tumor xenografts in each group of nude mice. *p < 0.05, **p < 0.01, ***p < 0.001