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Fig. 1 | Cancer Cell International

Fig. 1

From: Salvianolic acid B targets mortalin and inhibits the migration and invasion of hepatocellular carcinoma via the RECK/STAT3 pathway

Fig. 1

Mortalin can promote the migration of hepatocellular carcinoma cells. A Western blot analyses of the expressions of E-cadherin, vimentin, N-cadherin, mortalin, Flag, and GAPDH in HCC cells with different mortalin levels. MMP2 and MMP9 activities were investigated by gelatin zymography assays. B HepG2 cells were subjected to the migration assays after overexpression of mortalin, and migrated cells were counted with Stat Monitor in Photoshop (mean ± SD, n = 3). *P < 0.05, statistically significant difference vs. untreated cells. Bars = 100 μm. C HCCLM3 cells were subjected to the migration assays after mortalin knockdown with siRNA, and migrated cells were counted with Stat Monitor in Photoshop (mean ± SD, n = 3). *P < 0.05, statistically significant difference vs. untreated cells. Bars = 100 μm

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Cancer Cell International

ISSN: 1475-2867

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