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Fig. 3 | Cancer Cell International

Fig. 3

From: Hypoxia-mediated YTHDF2 overexpression promotes lung squamous cell carcinoma progression by activation of the mTOR/AKT axis

Fig. 3

YTHDF2 knockdown inhibits cell proliferation and invasion in LUSC. A The western blot analyzed the expression of mTOR/AKT-related proteins in NCI-H226 and SK-MES-1 cells. B and C NCI-H226 and SK-MES-1 had YTHDF2 knocked out, resulting in significant inhibition of cell proliferation, migration and invasion. D YTHDF2 knockdown significantly inhibits cell migration viability in NCI-H226 and SK-MES-1 cells by the wound-healing assay. Data are represented by the mean ± SD of three independent experiments. *P < 0.05 vs. the vector group

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Cancer Cell International

ISSN: 1475-2867

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