Fig. 1
From: MiR-155-5p suppresses SOX1 to promote proliferation of cholangiocarcinoma via RAF/MEK/ERK pathway
SOX1 is down-regulated in CCA tissues. A Box plots of SOX1 expression in cholangiocarcinoma (CCA) tissues compared to normal bile duct tissues. Data sourced from GEO databases GSE32225 (A) and GSE76297 (B). ***p < 0.001, ****p < 0.0001. B Representative IHC images showing SOX1 expression in normal bile duct tissue and CCA tissue specimens. Upper panel shows the overall view of the entire section. Scale bars are shown. The SOX1 expression were examined by semiquantitatively analyzed. **p < 0.01. C Results of Western blotting showing the expression levels of SOX1 protein in nine CCA tissue specimens and four normal bile duct tissue specimens. N normal bile duct tissues; C CCA tissues