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Fig. 2 | Cancer Cell International

Fig. 2

From: Cervical cancer-derived exosomal miR-663b promotes angiogenesis by inhibiting vinculin expression in vascular endothelial cells

Fig. 2

VCL is the direct target of miR-663b. A The putative binding site between VCL and miR-663b. B The survival curve of cervical cancer associated with miR-663b levels. C miR-663b expression levels in 25 normal cervical tissues and 51 tumor tissues were determined by qPCR. D The correlations between the expression of VCL and miR-663b. E Luciferase activity was detected in 293T cells cotransfected with miR-663b mimics or miRNA NC and WT-VCL or MUT-VCL or empty vector. *P < 0.05, **P < 0.01, ***P < 0.001. VCL, vinculin; CON, control; WT, wild-type; MUT, mutant

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