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Fig. 5 | Cancer Cell International

Fig. 5

From: Cervical cancer-derived exosomal miR-663b promotes angiogenesis by inhibiting vinculin expression in vascular endothelial cells

Fig. 5

Exosomal miR-663b promotes angiogenesis in-vivo. A Comparison of the tumors (CaSki) taken from the Exo-miR-663b up, Exo-up NC, Exo-miR-663b inh, Exo-inh NC groups. An equal volume of PBS was injected as a blank control. B Growth curves of tumors were generated by measuring tumor volumes every three days (n = 6). C Analysis of tumor weight in each group (n = 6). D IHC was performed to measure the expression level of VCL in tumors (CaSki) taken from the Exo-miR-663b up, Exo-up NC, Exo-miR-663b inh, Exo-inh NC groups. E IHC was performed to demonstrate the existence of endothelial tissue and to assess tumor angiogenesis using a CD31 antibody. *P < 0.05, **P < 0.01 and ***P < 0.001. VCL, vinculin

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