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Fig. 7 | Cancer Cell International

Fig. 7

From: TKTL1 participated in malignant progression of cervical cancer cells via regulating AKT signal mediated PFKFB3 and thus regulating glycolysis

Fig. 7

TKTL1 was involved in proliferation, invasion and migration of CC cells by regulating AKT and thus activating PFKFB3 rather than HK2. A CCK-8 detected the cell viability after cell transfection. B Wound healing detected the migration of cells after transfection. C Transwell detected the invasion of cells after transfection. D Statistical diagram of cell migration. E Statistical diagram of cell invasion. F Western blot detected the expression of TIMP1, MMP14 and MMP9. ***p < 0.001 vs shRNA-TKTL1; #p < 0.05, ##p < 0.01, ###p < 0.001 vs shRNA-TKTL1 + SC-79 + shRNA-NC

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Cancer Cell International

ISSN: 1475-2867

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