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Fig. 5 | Cancer Cell International

Fig. 5

From: A reciprocal feedback of miR-548ac/YB-1/Snail induces EndMT of HUVECs during acidity microenvironment

Fig. 5

YB-1 is indispensable for miR-548ac deficiency-induced EndMT in HUVECs under acidic conditions. In the acidic medium (pH 6.8), after HUVECs were transfected with miR-548ac mimics alone or co-transfected with YB-1 overexpression plasmid. a The expression of VE-cadherin, CD31, α-SMA, and Vimentin were measured at mRNA and protein levels, respectively. b The morphology, wound-healing, and transwell migration assay of HUVECs were performed as indicated. Histograms are the statistical result of the corresponding wound-healing and transwell migration assay

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Cancer Cell International

ISSN: 1475-2867

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