Table 1 miR-378d expression in ESCC patients and its clinicpathological significance, 596 case
From: miR-378d suppresses malignant phenotype of ESCC cells through AKT signaling
Clinical information | miR-378dLow | miR-378dHigh | total | χ2 | P |
|---|---|---|---|---|---|
N (%) | N (%) | ||||
Age(years) | |||||
≥ 61 | 198(63.06) | 116(36.94) | 314 | 1.220 | 0.269 |
< 61 | 190(67.38) | 92(32.62) | 282 | ||
Gender | |||||
Male | 299(65.28) | 159(34.72) | 458 | 0.029 | 0.864 |
Female | 89(64.49) | 49(35.08) | 138 | ||
Tumor size(cm) | |||||
> 4 | 143(65.90) | 74(34.10) | 217 | 0.096 | 0.757 |
≤ 4 | 245(64.64) | 134(35.36) | 379 | ||
Stage | |||||
I + II | 112(68.29) | 52(31.71) | 164 | 1.052 | 0.305 |
III + IV | 275(63.81) | 156(36.19) | 431 | ||
LNM | |||||
Negative | 199(63.17) | 116(36.83) | 315 | 1.091 | 0.296 |
Positive | 189(67.26) | 92(32.74) | 281 | ||
Nerve invasion | |||||
Negative | 343(66.22) | 175(33.78) | 518 | 2.168 | 0.141 |
Positive | 45(57.69) | 33(42.31) | 78 | ||
Vascular invasion | |||||
Negative | 359(64.80) | 195(35.20) | 554 | 0.310 | 0.578 |
Positive | 29(69.05) | 13(30.95) | 42 | ||
Differentiation | |||||
High | 206(64.58) | 113(35.42) | 319 | 2.778 | 0.249 |
Middle | 173(64.79) | 94(35.21) | 267 | ||
Low | 9(90.00) | 1(10.00) | 10 | ||
Tumor location | |||||
Up | 105(68.18) | 49(31.82) | 154 | 2.534 | 0.282 |
Middle | 179(63.03) | 105(36.97) | 284 | ||
Down | 9(81.82) | 2(18.18) | 11 | ||
Invasion depth | |||||
Mucous layer | 19(82.61) | 4(17.39) | 23 | 4.588 | 0.101 |
Muscle layer | 101(68.24) | 47(31.76) | 148 | ||
Whole layer | 267(62.97) | 157(37.03) | 424 | ||