Fig.6

miR-216a-5p serves as an important mediator of FDFT1 upregulation induced by GS. a qRT-PCR analysis to show the relative expression of miR-216a-5p in MGC-803 and HGC-27 cells under the normal glucose condition or GS condition, respectively. b Cell counting assay to show proliferation of MGC-803 and HGC-27 cells transfected with negative control or miR-216a-5p mimics under normal glucose condition or GS condition, respectively. c CCK-8 assay to show proliferation of MGC-803 and HGC-27 cells as in (b). d EdU assay to show proliferation of MGC-803 cells and HGC-27 cells as in (b). Histograms are on the right. Scale bar: 100 mm. e Wound healing assay to show migration of MGC-803 and HGC-27 cells as in (b). Histograms are on the right. f Transwell assay to show invasion of MGC-803 and HGC-27 cells as in (b). Histograms are on the right. Scale bar: 100 mm. Data are presented as means ± SD. *P < 0.05, **P < 0.01, ***P < 0.001