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Fig. 7 | Cancer Cell International

Fig. 7

From: LncRNA TP73‐AS1 promotes nasopharyngeal carcinoma progression through targeting miR-342-3p and M2 polarization via exosomes

Fig. 7

TP73-AS1 is transferred by exosomes to promote M2 polarization. A mRNA expressions of M1 and M2 markers in macrophages treated with LPS/INF-γ or IL-4/IL-13. B Expression of TP73-AS1 in M0, M1, and M2 macrophages. C mRNA expressions of M1 and M2 markers in macrophages with TP73-AS1 knockdown. D mRNA expressions of M1 and M2 markers in macrophages with TP73-AS1 overexpression. E Expressions of TP73-AS1 and M2 markers in macrophages treated with conditioned medium of TP73-AS1-overexpression CNE-2 cells. F Expressions of exosomal markers in exosomes derived from CNE-2 cells, as illustrated by western blotting. G Morphology and size distribution of exosomes derived from CNE-2 cells, as illustrated by transmission electron microscopy and nanoparticle tracking analysis (Scalar bar = 100 μm). H Level of exosomal TP73-AS1 derived from CNE-2 cells with TP73-AS1 overexpression or knockdown (*p < 0.05; **p < 0.01 and ***p < 0.001)

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Cancer Cell International

ISSN: 1475-2867

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