Table 1 General and clinical characteristics of BL patients with high or low DHX15 expression
From: RNA helicase DHX15 decreases cell apoptosis by NF-κB signaling pathway in Burkitt lymphoma
NO. case | High DHX15 (%) | Low DHX15 (%) | P | |
|---|---|---|---|---|
Age | ||||
< 14 years (%) | 15 | 5 (33.3) | 10 (66.7) | 0.347 |
≥ 14 years (%) | 16 | 8 (50) | 8 (50) | |
Gender | ||||
Male (%) | 28 | 11 (39.3) | 17 (60.7) | 0.361 |
Female (%) | 3 | 2 (66.7) | 1 (33.3) | |
WBC count | ||||
≥ 10 × 109/L (%) | 9 | 3 (33.3) | 6 (66.7) | 0.626 |
< 10 × 109/L (%) | 21 | 9 (42.9) | 12 (57.1) | |
Anemia | ||||
Yes (%) | 13 | 4 (30.8) | 9 (69.2) | 0.367 |
No (%) | 17 | 8 (47.1) | 9 (52.9) | |
PLT count | ||||
≥ 100 × 109/L (%) | 24 | 9 (37.5) | 15 (62.5) | 0.576 |
< 100 × 109/L (%) | 6 | 3 (50) | 3 (50) | |
Albumin < 35 g/L | ||||
Yes (%) | 12 | 3 (25) | 9 (75) | 0.171 |
No (%) | 18 | 9 (50) | 9 (50) | |
LDH > 245U/L | ||||
Yes (%) | 22 | 9 (40.9) | 13 (59.1) | 0.382 |
No (%) | 5 | 1 (20) | 4 (80) | |
UA > 420 μmol/L | ||||
Yes (%) | 15 | 5 (33.3) | 10 (66.7) | 0.597 |
No (%) | 14 | 6 (42.9) | 8 (57.1) | |
EBER ISH ( +) | ||||
Yes (%) | 9 | 4 (44.4) | 5 (55.6) | 0.402 |
No (%) | 8 | 2 (25) | 6 (75) | |
B symptoms | ||||
Yes (%) | 10 | 3 (30) | 7 (70) | 0.429 |
No (%) | 20 | 9 (45) | 11 (55) | |
Stage | ||||
I–II | 5 | 2 (40) | 3 (60) | 1.0 |
III–IV | 20 | 8 (40) | 12 (60) | |
Tumor diameter ≥ 10 cm | ||||
Yes (%) | 4 | 2 (50) | 2 (50) | 0.683 |
No (%) | 18 | 7 (38.9) | 11 (61.1) |