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Fig. 1 | Cancer Cell International

Fig. 1

From: SHC4 promotes tumor proliferation and metastasis by activating STAT3 signaling in hepatocellular carcinoma

Fig. 1

SHC4 expression is upregulated in HCC tissues and associated with poor prognosis of HCC patients. A Representative images of IHC staining for SHC4 in 105 paired HCC tumor and adjacent normal tissues. Scale bar, 400 μm (left panel) or 50 μm (right panel). B Dot density plot shows the distribution of average IOD for SHC4 level in the samples from A. ***P < 0.001, Paired t test. C Kaplan–Meier curves of disease-free survival rate of 105 HCC patients with SHC4 high or low expression levels. P  = 0.0197, log-rank test. D Kaplan–Meier curves of overall survival rate of 105 HCC patients with SHC4 high or low expression levels. P  = 0.0390, log-rank test

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