Fig. 1

a The molecular structure of niraparib. b Cells were incubated with niraparib (0, 2.5, 5, 10, 20, 40 μM) for 24 and 48 h, and the proliferation rate was determined by the CCK-8 assay. c, d SKOV3 and A2780 cells were treated with niraparib at various concentrations (0, 2.5, 5, 10 μM) for 48 h, and the expression of PARP-1 protein was detected by western blot analysis. GAPDH protein was used as a loading control. GAPDH protein was used as a loading control. Data represent the mean ± SD of three independent experiments. ***P < 0.001, **P < 0.01, *P < 0.05