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Fig. 6 | Cancer Cell International

Fig. 6

From: The functions and prognostic value of Krüppel‐like factors in breast cancer

Fig. 6

KLF2 and KLF15 inhibits breast cancer proliferation and migration in vitro. A The mRNA expression levels of KLF2 and KLF15 in breast cancer cell lines and normal breast cell line MCF10A determined by RT-qPCR. B The protein expression levels of KLF2 and KLF15 in breast cancer cell lines and normal breast cell line MCF10A determined by western blot. C The expression of KLF2 and KLF15 in KLF2 or KLF15 expressing plasmid transfected MDA-MB-231 cells determined by western blot. D Cell viability of KLF2-overexpressed (a) or KLF15-overexpressed (b) MDA-MB-231 cells, as well as control cells determined by MTT analysis. E Colony formation analysis of KLF2-overexpressed (a) or KLF15-overexpressed (b) MDA-MB-231 cells, as well as control cells. F, Edu analysis of KLF2-overexpressed (a) or KLF15-overexpressed (b) MDA-MB-231 cells, as well as control cells. G Transwell analysis of KLF2-overexpressed (a) or KLF15-overexpressed (b) MDA-MB-231 cells, as well as control cells. H Scratch analysis of KLF2-overexpressed or KLF15-overexpressed MDA-MB-231 cells, as well as control cells. ***P < 0.001

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