Skip to main content
Fig. 2 | Cancer Cell International

Fig. 2

From: Identification of a novel HOOK3-FGFR1 fusion gene involved in activation of the NF-kappaB pathway

Fig. 2

Clinical presentation of the patient with the HOOK3-FGFR1 fusion gene. a The entire treatment process of the HOOK3-FGFR1 positive patient. b Wright stain of bone marrow aspirate smear from Case 1, with blast cells clearly seen in the primary and NR specimens. c Karyotype analysis showed complex abnormalities and one additional ring chromosome (indicated by the red arrow). d Flow cytometry analysis of immunophenotypic markers for the HOOK3-FGFR1 positive patient. Total cells are gated on SSC/FSC plot where viable cells are selected for following analysis. The bone marrow cells of this patient were labeled with monoclonal antibody CD45. The diagnosis stage flow results showed the blast cells were positive for CD117 and CD34 (myeloblasts: 2.43%), and positive for CD19 and cLambda (monoclonal B-lymphoid cells: 11%)

Back to article page