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Fig. 2 | Cancer Cell International

Fig. 2

From: Comprehensive analysis of N6-methyladenosine regulators with the tumor immune landscape and correlation between the insulin-like growth factor 2 mRNA-binding protein 3 and programmed death ligand 1 in bladder cancer

Fig. 2

Profiles of expression levels of 24 m6A methylation regulators in BCa and adjacent normal tissues. A Heatmap of m6A RNA expression levels in BCa and normal tissues from The Cancer Genome Atlas (TCGA) and Genotype Tissue Expression project (GTEx) databases. B Box plots of m6A RNA expression levels of the tumor and normal tissues. C Spearman correlation analysis of the m6A regulators in BCa. Red dot represents positive correlation and blue dot represents negative correlation. D The interaction among m6A regulators in BCa. Brown dots represent the writers, red dots represent the erasers, and yellow dots represent the readers. The lines linking regulators show their interactions, while the thickness and color show the correlation strength between the regulators. Low interaction is marked with thin orange lines, while positive correlation is marked with blue thick lines. E The protein levels of m6A regulators detected by immunohistochemistry staining were from The Human Protein Atlas database

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