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Fig. 6 | Cancer Cell International

Fig. 6

From: Pan-cancer analysis combined with experiments explores the oncogenic role of spindle apparatus coiled-coil protein 1 (SPDL1)

Fig. 6

Enrichment analysis of SPDL1. A PPI network of top 50 genes related to the expression of SPDL1. B The top 100 SPDL1-correlated genes in TCGA and the correlation between SPDL1 and selected targeting genes, including SGOL2, ZWILCH, HMMR, SHCBP1, PLK4. C The corresponding heatmap in the cancer types of TCGA. D The analysis of the SPDL1 interaction and correlated genes. E Bubble plot for KEGG enrichment analysis. F Bubble plot for GO enrichment analysis of top 10 terms. G GSEA for SPDL1 in LUAD and LUSC based on GO gene sets. P < .05 was considered significant. KEGG: Kyoto encyclopedia of genes and genomes; GO: Gene Ontology; BP: biological processes; CC: cell component; MF: molecular function. GSEA: Gene set enrichment analysis

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