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Fig. 4 | Cancer Cell International

Fig. 4

From: Correction to: Exosomal lncRNA SNHG10 derived from colorectal cancer cells suppresses natural killer cell cytotoxicity by upregulating INHBC

Fig. 4

EMT exosomal lncRNA SNHG10 inhibited NK cell cytotoxicity. A The efficacy of the overexpression of the lncRNA SNHG10 in SW480 cells was verified by qRT-PCR. B The viability of NK92-MI cells was detected by CCK-8 assay. C The cytotoxicity of NK92-MI cells (pretreated with EMT-exo or not) co-cultured with SW480 cells was detected by LDH assay. D The production of IFN-γ from NK92-MI cells was detected by ELISA. The expression of the toxic molecules perforin and granzyme B in NK92-MI cells (pretreated with EMT-exo or not) co-cultured with SW480 cells was measured by qRT-PCR (E, F), western blotting (G), and immunofluorescence (H). GAPDH was used to normalize gene expression. t-test, *P < 0.05, **P < 0.01, ***P < 0.001

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Cancer Cell International

ISSN: 1475-2867

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