Fig. 4
From: Antitumor responses in gastric cancer by targeting B7H3 via chimeric antigen receptor T cells
B7H3 expression positively correlates with the tumor stemness. A TCGA analysis showed that B7H3 significantly correlates cancer stem cell makers. B RT-PCR analysis showed that B7H3 significantly correlates cancer stem cell makers. C The expression of PROM1 was significantly decreased in AGS cells when B7H3 was knocked down (****P < 0.0001). D The expression of PROM1 was significantly up-regulated in NCI-N87 cells when B7H3 was overexpression (****P < 0.0001). E Protein levels of B7H3 and CD133 when the expression of B7H3 was changed. F The effect of B7H3 on sphere-forming ability of tumor cells (**P < 0.01)