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Fig. 2 | Cancer Cell International

Fig. 2

From: ERBB3 binding protein 1 promotes the progression of malignant melanoma through activation of the Wnt/ β-catenin signaling pathway

Fig. 2

Ebp1 knockdown suppresses the proliferation of malignant melanoma. a Ebp1 p48 was expressed in the HacaT, A375 and B16 cells (***p < 0.001, *p < 0.05, vs. HacaT). b, c Ebp1 was knocked down in A375 and B16 cells and detected by Western blotting (****p < 0.0001, vs. shNC). d Cell proliferation was measured by CCK-8 assay (**p < 0.01, *p < 0.05, vs. shNC). e Ebp1 knockdown suppressed the colony-forming capacity of A375 and B16 cells by colony-formation assay (***p < 0.001, ****p < 0.0001, vs. shNC). f Effects of Ebp1 knockdown on cell cycle profile in A375 and B16 cells using flow cytometry (****p < 0.0001, ***p < 0.001, **p < 0.01, *p < 0.05, vs. shNC)

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Cancer Cell International

ISSN: 1475-2867

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