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Fig. 5 | Cancer Cell International

Fig. 5

From: DDX10 promotes the proliferation and metastasis of colorectal cancer cells via splicing RPL35

Fig. 5

DDX10 alternatively splices the mRNA of RPL35 then work through E2F pathway or immune response of CRC A RPL35 interacts with DDX10 through the result of Co-IP; B Overexpression of DDX10 obviously reduced the expression of RPL35 at mRNA level via q-PCR; C Overexpression of DDX10 obviously reduced the expression of RPL35 at protein level; D The expression of two mRNA isoforms of RPL35 in normal HCT116 cells and DDX10 knockdown HCT116 cells by q-PCR; E DDX10 and RPL35 are closely related to E2F1 and E2F4 from the data of LinkedOmics; F DDX10 interacts with RPL35 to regulate E2F1 and E2F4 to regulate colorectal cancer; G The relationship between DDX10 and immune cells that infiltrate the tumor tissue in COAD

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