Prognostic value of maximum standard uptake value, metabolic tumour volume, and total lesion glycolysis of 18F-FDG PET/CT in patients with malignant pleural mesothelioma: a systematic review and meta-analysis

Table 2 Subgroup of OS of SUV max

End point	Volumetric parameters	Factor	No. of studies	Heterogeneity test (I², P)	Effect model	HR	95%CI of HR	Conclusion
OS	SUV max	Study design
		P	2	0.0, 0.487	Fixed	1.05	1.03,1.08	Significant
		R	9	26.9, 0.205	Fixed	1.69	1.39,2.07	Significant
		Cut off method
		ROC	2	35.8,0.212	Fixed	2.58	1.37,4.86	Significant
		Others	9	65.8,0.003	Random	1.22	1.07,1.38	Significant
		Threshold
		≥ 8.1	6	69.9,0.005	Random	1.14	1.01,1.30	Significant
		< 8.1	5	0.0,0.619	Fixed	1.80	1.35,2.39	Significant

HR hazard ratio, CI confidence interval, OS overall survival, SUV Max maximum standard uptake value, R retrospective, P prospective, ROC receiver operating characteristic

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