Fig. 7
From: A pan-cancer analysis of molecular characteristics and oncogenic role of gasdermins
The expression of GSDME was correlated with Micro Vessel density (MVD) and GSDME promoted the invasive and migratory abilities of colon cancer cells in vitro. A The GSDME was overexpressed in HCT116 and SW480 cells. B Transwell assays in control and GSDME-overexpression SW480 cells. C Transwell assays in control and GSDME-overexpression HCT116 cells. D Migration of control or GSDME-overexpression HCT-116 and SW480 cells were determined by wounding-healing assay. E The MVD was positively correlated with GSDME expression in CRC tissue. All data were presented as the mean ± SD from three independent experiments. *P < 0.05, ** P < 0.01, ***P < 0.001