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Table 2 Correlation between CPNE1 mRNA expression and PFS and DSS in HCC based on different clinical parameters by Kaplan–Meier plotter

From: CPNE1 is a potential prognostic biomarker, associated with immune infiltrates and promotes progression of hepatocellular carcinoma

Clinical characteristics

PFS (N = 370)

DSS (N = 362)

N

HR

P-value

N

HR

P-value

Gender

      

 Female

121

2.11 (1.26–3.53)

0.038

118

2.06 (0.98–4.33)

0.051

 Male

249

0.64 (0.43–0.94)

0.023

244

2.06 (1.16–3.64)

0.011

Stage

      

 I

171

1.32 (0.78–2.25)

0.3

168

1.71 (0.69–4.22)

0.24

 II

85

0.53 (0.28–1.02)

0.052

83

3.37 (1.13–10.06)

0.021

 III

85

2.15 (1.2–3.82)

0.0082

83

2.97 (1.41–6.26)

0.0029

 IV

5

NA

NA

3

NA

NA

Grade

      

 1

55

3.83 (1.67–8.75)

0.00069

55

3.24 (0.91–11.53)

0.056

 2

177

1.65 (1.05–2. 6)

0.03

171

2.31 (1.17–4.54)

0.013

 3

121

0.72 (0.43–1.21)

0.21

119

2.07 (0.93–4.61)

0.068

 4

12

NA

NA

12

NA

NA

Hepatitis virus

      

 Yes

153

0.63 (0.39–1.03)

0.066

151

1.85 (0.81–4.23)

0.14

 None

169

2.4 (1.54–3.75)

7.7e−05

165

2.52 (1.37–4.65)

0.0022

Alcohol consumption

 Yes

117

0.62 (0.35–1.1)

0.099

117

2.5 (1.16–5.41)

0.016

 None

215

1.68 (1.13–2.52)

0.01

199

2.9 (1.48–5.7)

0.0012

  1. PFS Progression Free Survival, DSS Disease Specific Survival, HR hazard ratio
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Cancer Cell International

ISSN: 1475-2867

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