Table 4 The relationships between CPNE1 expression and immune markers in LIHC (TIMER)

CD8 + T cell

CD8A

1.37E−05

7.86E−09

CD8B

8.78E−06

1.97E−08

T cell (general)

CD3D

7.86E−08

3.02E−11

CD3E

1.36E−06

4.07E−12

CD2

8.58E−07

1.62E−11

B cell

CD19

6.58E−06

1.51E−06

CD79A

1.20E−06

7.89E−10

Monocyte

CD86

5.30E−08

3.09E−13

CD115 (CSF1R)

2.85E−04

2.13E−07

TAM

CCL2

8.51E−03

3.87E−04

CD68

1.06E−07

2.76E−10

IL10

7.82E−06

1.10E−08

M1 Macrophage

INOS (NOS2)

4.85E−01

3.36E−01

IRF5

5.17E−10

2.59E−09

COX2(PTGS2)

2.07E−03

1.11E−05

M2 Macrophage

CD163

1.18E−01

9.00E−03

VSIG4

2.53E−01

4.35E−02

MS4A4A

8.79E−02

2.79E−03

Neutrophils

CD66b(CEACAM8)

1.65E−01

8.98E−02

CD11b (ITGAM)

1.70E−02

4.60E−03

CCR7

1.35E−04

3.55E−08

Natural killer cell

KIR2DL1

9.50E−01

8.18E−01

KIR2DL3

4.34E−03

1.54E−03

KIR2DL4

1.51E−02

4.56E−03

KIR3DL1

5.04E−01

3.63E−01

KIR3DL2

3.99E−03

4.73E−04

KIR3DL3

8.09E−01

7.63E−01

KIR2DS4

1.47E−01

1.04E−01

Dendritic cell

HLA-DPB1

1.85E−05

1.91E−08

HLA-DQB1

1.90E−03

2.23E−05

HLA-DRA

9.37E−04

8.11E−06

HLA-DPA1

3.48E−04

6.66E−07

BDCA-1(CD1C)

1.19E−08

1.02E−11

BDCA-4(NRP1)

4.11E−12

6.60E−12

CD11c (ITGAX)

1.77E−07

9.01E−11

Th1

T-bet (TBX21)

1.91E−03

7.87E−06

STAT4

2.42E−04

3.35E−05

STAT1

2.56E−11

1.98E−13

IFN-γ (IFNG)

2.47E−05

9.20E−07

TNF-α (TNF)

3.49E−09

4.90E−13

Th2

GATA3

6.17E−07

5.58E−11

STAT6

3.85E−02

4.95E−02

STAT5A

1.13E−10

2.58E−12

IL13

1.40E−01

2.25E−01

Tfh

BCL6

3.47E−05

1.01E−04

IL21

9.91E−02

2.63E−02

Th9

TGFBR2

2.99E−05

4.43E−06

IRF4

3.05E−08

2.38E−12

PU.1(SPI1)

3.08E−09

3.28E−15

Th17

STAT3

2.21E−01

1.34E−01

IL17A

1.20E−02

3.64E−03

Th22

CCR10

2.74E−12

6.31E−12

Treg

FOXP3

3.38E−02

5.35E−03

CCR8

3.01E−06

3.28E−08

STAT5B

9.95E−09

6.90E−08

TGFβ (TGFB1)

2.25E−11

7.02E−15

T cell exhaustion

PD-1 (PDCD1)

3.63E−10

1.09E−13

CTLA4

1.39E−09

2.65E−13

LAG3

2.67E−09

4.12E−11

TIM-3 (HAVCR2)

1.63E−06

5.67E−11

GZMB

2.13E−03

1.95E−04