Fig. 3
From: DFNA5 regulates immune cells infiltration and exhaustion
Correlation of DFNA5 expression with tumour-infiltrating lymphocytes in COAD (colon adenocarcinoma), LIHC (hepatocellular carcinoma), and LUAD (lung adenocarcinoma). A DFNA5 expression is significantly negatively related to tumour purity and has significant positive correlations with infiltrating levels of CD8 + T cells, CD4 + T cells, macrophages, neutrophils, and dendritic cells in COAD but not B cells. B DFNA5 expression has significant correlations with tumour purity and infiltrating levels of B cells, CD8 + T cells, CD4 + T cells, macrophages, neutrophils, and dendritic cells in LIHC. C DFNA5 expression is significantly negatively related to tumour purity and has significant positive correlations with infiltrating levels of B cells, CD8 + T cells, CD4 + T cells, macrophages, neutrophils, and dendritic cells in LUAD. D The increased content of Flag-DFNA5 plasmids co-transfected with 3x-myc-PDCD1 or 3x-myc-CD274 plasmid, the expression levels of FLAG, 3x-myc and β-actin were detected by western blot. The band grey value of the rightmost well of 3x-myc-PDCD1 or 3x-myc-CD274 relative to the corresponding beta-actin were set at 1.0. The other treatments were compared with them