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Table 2 Correlation analysis between DFNA5 and relate genes and markers of monocyte and macrophages in GEPIA

From: DFNA5 regulates immune cells infiltration and exhaustion

Description

Gene markers

COAD

LIHC

LUAD

Tumor

Nomal

Tumor

Nomal

Tumor

Nomal

R

P

R

P

R

P

R

P

R

P

R

P

Monocyte

CD86

0.74

***

− 0.15

0.34

0.33

***

0.41

*

0.23

***

0.25

0.057

CD115 (CSF1R)

0.78

***

− 0.032

0.84

0.37

*

0.29

***

0.26

***

0.33

*

TAM

CCL2

0.65

***

0.19

0.24

0.13

0.016

0.44

*

0.24

*

− 0.06

0.65

CD68

0.67

***

0.51

***

0.31

***

0.46

***

0.17

***

0.22

0.1

IL10

0.45

***

− 0.069

0.67

0.26

***

0.51

***

0.2

***

0.33

*

M1 Macrophage

INOS (NOS2)-0.13

 

0.033

− 0.1

0.52

− 0.033

0.53

0.45

***

0.0074

0.087

− 0.13

0.33

IRF5

0.3

0.033

0.09

0.58

0.17

*

0.26

0.063

0.16

***

0.29

0.024

COX2 (PTGS2)0.24

 

***

0.0068

0.97

0.15

*

0.41

*

0.076

0.095

− 0.11

0.39

M2 Macrophage

CD163

0.61

***

− 0.036

0.82

0.22

***

0.25

0.082

0.2

***

0.27

0.037

VSIG4

0.76

***

− 0.029

0.86

0.23

***

0.25

0.084

0.19

***

− 0.039

0.77

MS4A4A

0.73

***

− 0.11

0.51

0.26

***

0.39

*

0.21

***

0.17

0.19

  1. LUAD lung adenocarcinoma, LIHC liver hepatocellular carcinoma, COAD colon adenocarcinoma, TAM tumor-associated macrophage. Normal, correlation analysis in normal tissue of TCGA. Tumor, correlation analysis in tumor tissue of TCGA. ***P < 0.0001,**P < 0.001, *P < 0.01