From: DFNA5 regulates immune cells infiltration and exhaustion
Description | Gene markers | COAD | LIHC | LUAD | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tumor | Nomal | Tumor | Nomal | Tumor | Nomal | ||||||||
R | P | R | P | R | P | R | P | R | P | R | P | ||
Monocyte | CD86 | 0.74 | *** | − 0.15 | 0.34 | 0.33 | *** | 0.41 | * | 0.23 | *** | 0.25 | 0.057 |
CD115 (CSF1R) | 0.78 | *** | − 0.032 | 0.84 | 0.37 | * | 0.29 | *** | 0.26 | *** | 0.33 | * | |
TAM | CCL2 | 0.65 | *** | 0.19 | 0.24 | 0.13 | 0.016 | 0.44 | * | 0.24 | * | − 0.06 | 0.65 |
CD68 | 0.67 | *** | 0.51 | *** | 0.31 | *** | 0.46 | *** | 0.17 | *** | 0.22 | 0.1 | |
IL10 | 0.45 | *** | − 0.069 | 0.67 | 0.26 | *** | 0.51 | *** | 0.2 | *** | 0.33 | * | |
M1 Macrophage | INOS (NOS2)-0.13 | 0.033 | − 0.1 | 0.52 | − 0.033 | 0.53 | 0.45 | *** | 0.0074 | 0.087 | − 0.13 | 0.33 | |
IRF5 | 0.3 | 0.033 | 0.09 | 0.58 | 0.17 | * | 0.26 | 0.063 | 0.16 | *** | 0.29 | 0.024 | |
COX2 (PTGS2)0.24 | *** | 0.0068 | 0.97 | 0.15 | * | 0.41 | * | 0.076 | 0.095 | − 0.11 | 0.39 | ||
M2 Macrophage | CD163 | 0.61 | *** | − 0.036 | 0.82 | 0.22 | *** | 0.25 | 0.082 | 0.2 | *** | 0.27 | 0.037 |
VSIG4 | 0.76 | *** | − 0.029 | 0.86 | 0.23 | *** | 0.25 | 0.084 | 0.19 | *** | − 0.039 | 0.77 | |
MS4A4A | 0.73 | *** | − 0.11 | 0.51 | 0.26 | *** | 0.39 | * | 0.21 | *** | 0.17 | 0.19 |