Fig. 3
From: MeCP2 confers 5-fluorouracil resistance in gastric cancer via upregulating the NOX4/PKM2 pathway
MeCP2 overexpression inhibited the 5-FU sensitivity of 5-FU-resistant GC cells. A, B Overexpressing efficiency of MeCP2 in 5-FU resistant GC cells transfected with MeCP2-overexpressing plasmid or empty plasmid. Cell viability (C, D), colony formation (E, F), cell cycle (G, H) and cell apoptosis (I, J) were detected in 5-FU resistant GC cells transfected with MeCP2-overexpressing plasmid or empty plasmid followed by 5-FU treatment (*p < 0.001, as compared with empty plasmid; #p < 0.001, as compared with empty plasmid + 5-FU; Student's t-test)