Table 4 Univariate and multivariate Cox regression analysis of overall survival in patients with esophageal squamous cell carcinoma
From: High AKAP8L expression predicts poor prognosis in esophageal squamous cell carcinoma
Variable | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
HR (95% CI) | p value | HR (95% CI) | p value | |
Gender (Female vs. Male) | 1.127 (0.665–1.911) | 0.656 |  |  |
Age (< 60 vs. ≥ 60) | 1.887 (1.242–2.866) | 0.003 | 1.682 (1.095–2.586) | 0.018 |
Differentiation grade (III vs. I–II) | 0.789 (0.497–1.253) | 0.315 |  |  |
T stage (T3–4 vs. T1–2) | 1.461 (0.920–2.320) | 0.108 |  |  |
N stage (N1–2 vs. N0) | 2.598 (1.695–3.982) |  < 0.0001 | 2.252 (1.206–4.208) | 0.011 |
M stage (M1 vs. M0) | 1.250 (0.544–2.873) | 0.599 |  |  |
Clinical stage (III–IV vs. I–II) | 1.980 (1.304–3.006) | 0.001 | 0.956 (0.524–1.744) | 0.883 |
AKAP8L expression (High vs. Low) | 2.588 (1.677–3.992) |  < 0.0001 | 2.208 (1.417–3.440) |  < 0.0001 |