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Fig. 1 | Cancer Cell International

Fig. 1

From: Circular RNA circ_IRAK3 contributes to tumor growth through upregulating KIF2A via adsorbing miR-603 in breast cancer

Fig. 1

Expression pattern of circ_IRAK3 in BC tissues and cells. A The expression of circ_IRAK3 in BC tissues (compared to adjacent non-cancerous tissues) was estimated by qRT-PCR. B Kaplan–Meier curves of overall survival for BC patients with high or low expression of circ_IRAK3. The cutoff value was the median of circ_IRAK3 expression in 47 BC patients, of which 23 were classified as low expression and 24 were classified as high expression. C Relative expression of circ_IRAK3 in BC cells (HCC70 and MDA-MB-231) (compared with MCF-10A cells) was evaluated by qRT-PCR. D, E The levels of circ_IRAK3 and IRAK3 mRNA in total RNA of HCC70 and MDA-MB-231 under RNase R treatment were analyzed by qRT-PCR. F, G Following the nuclear-cytoplasmic fractionation assay, the abundance of circ_IRAK3 in the nuclear and cytoplasmic portions was analyzed by qRT-PCR. *P  < 0.05

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Cancer Cell International

ISSN: 1475-2867

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