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Fig. 2 | Cancer Cell International

Fig. 2

From: ZHX2 inhibits thyroid cancer metastasis through transcriptional inhibition of S100A14

Fig. 2

ZHX2 restrains the migration of thyroid cancer cells. A The protein levels of ZHX2 in BHT101, BHP10-3, 8305C and KMH-2 cells were examined by WB. B EMT-related proteins N-cadherin, E-cadherin and vimentin were assayed in ZHX2-overexpressing KMH-2 and BHT101 cells or ZHX2-knockdown BHP10-3 and 8305C cells by WB. Thyroid cancer cells with the indicated manipulation were used to determine the migratory ability by using Transwell (C, D) and wound healing assays (E). The migrated cells were photographed. Image magnifications: 100 ×  (C, D), 40 ×  (E). Bar: 200 μm (C, D), 500 μm (E). Representative pictures are shown. Data are presented as the mean ± SD. Student’s t test, *p  < 0.05, **p  < 0.01

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