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Fig. 3 | Cancer Cell International

Fig. 3

From: ZHX2 inhibits thyroid cancer metastasis through transcriptional inhibition of S100A14

Fig. 3

ZHX2 inhibits S100A14 expression in thyroid cancer. A Correlations between ZHX2 and S100A14 mRNAs were analysed using the cBioPortal thyroid cancer dataset. B RT–qPCR analysis was used to determine the relationship between ZHX2 and S100A14 mRNAs in human specimens. C ZHX2 and S100A14 immunostaining was performed in thyroid para-tumour tissues and thyroid tumour tissues. Representative images are displayed (Image magnifications of 100 × , bar: 100 μm, left). Statistical analysis of ZHX2 and S100A14 correlation in samples (right). D S100A14 expression was determined in thyroid para-tumour tissues and thyroid tumour tissues from GEPIA datasets. E Kaplan–Meier relapse-free survival of thyroid cancer patients with S100A14 is presented. Data are presented as the mean ± SD. Student’s t test, *p < 0.05. A, B Pearson’s correlation coefficients (r) and p values (p) for two-sided correlation tests are shown

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