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Figure.3. | Cancer Cell International

Figure.3.

From: Long non-coding RNAs as the critical regulators of epithelial mesenchymal transition in colorectal tumor cells: an overview

Figure.3.

Role of lncRNAs in regulation of EMT-related transcription factors in CRC. Snail/Slug were inhibited by miR-149-3p and HOTAIR, while induced by LDLRAD4-AS1, EWSAT1, and PANDAR. Twist1 was activated by PANDAR, while suppressed by miR-149-3p and miR-489. ZEB1/2 was mainly inhibited by various microRNAs such as miR-217, miR-215, and miR-203. HIF-1α was also suppressed by miR-93-3p and CPS1-IT. (Created with www.BioRender.com)

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Cancer Cell International

ISSN: 1475-2867

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