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Fig. 2 | Cancer Cell International

Fig. 2

From: miR-30a targets STOX2 to increase cell proliferation and metastasis in hydatidiform moles via ERK, AKT, and P38 signaling pathways

Fig. 2

The effect of different expression levels of STOX2 on the proliferation and metastasis of trophoblastic cells. A and C Relative STOX2 expression was detected using qRT-PCR in JAR and HTR-8 cells transfected with STOX2 siRNA/negative control or STOX2 cDNA/negative control. B and D The effect of different STOX2 levels on JAR and HTR-8 cell proliferation in each group. E and F Colony formation ability of cells expressing different levels of STOX2. G and H Experiment of Edu in JAR and HTR-8 cells transfected with STOX2 siRNA or STOX2 cDNA. The last line is the positive control. Transwell assay migration (I and J) and invasion (K and L) abilities of the different groups of cells. Bar = 100 μm. *P < 0.05, **P < 0.01

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