Fig. 1From: Application of CRISPR/Cas9-based mutant enrichment technique to improve the clinical sensitivity of plasma EGFR testing in patients with non-small cell lung cancerSchematic diagram of CRISPR-CPPC assay. CRISPR-CPPC comprises three steps: (1) cfDNA PCR, (2) assembly of post-PCR cfDNA and Cas9 complex, (3) enrichment of target DNA template. After CRISPR-CPPC, the target DNA can be detected using a variety of downstream applications, such as ddPCRBack to article page