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Table 1 Main characteristics of studies exploring the relationship between SIRT6 expression and tumor prognosis

From: Clinicopathological and prognostic value of SIRT6 in patients with solid tumors: a meta-analysis and TCGA data review

Authors

Year

Region

Cancer type

Stage/ Grade

No. of Patients

Follow-up Time Median (range)

Detection Method

Outcomes

Location

NOS Score

Zhang [14]

2020

Korea

OS

I–IV

37

NR

IHC (CST)

OS, DFS

NR

8

Han [15]

2019

China

HCC

NR

120

60 M

IHC (Bioss)

OS, DFS

NR

7

Bae [16]

2018

Korea

OC

I–IV

104

82 M(1–209)

IHC (CST)

OS, DFS

Nu

8

Tian [10]

2018

China

CRC

I–IV

90

NR

IHC (CST)

OS

Nu

7

Li [17]

2018

China

CRC

I–IV

97

NR

IHC (Abcam)

OS

Nu

7

Zhu [18]

2018

China

NSCLC

I–IV

86

51 M

IHC (Abcam)

OS, DFS

Nu

6

Chen [4]

2017

China

NSCLC

I–III

122

44 M(1–60)

IHC (Abcam)

OS

Cy

7

Zhou [19]

2017

China

GC

I–IV

68

NR

IHC (CST)

OS, DFS

NR

6

Bai [11]

2016

China

NSCLC

I–IV

174

30 M(0–120)

IHC (Abcam)

OS

NR

5

Bae [20]

2016

Korea

BRC

I–IV

142

148.8 M(7.7–198.6)

IHC (Lifespan)

OS, DFS

Nu

7

Kugel [9]

2016

USA

PDAC

NR

120

33 M

IHC (NR)

OS

NR

9

Ran [21]

2016

China

HCC

I–III

53

NR

IHC (Novus)

OS

NR

8

Azuma [22]

2015

Japan

NSCLC

I–IV

98

NR

IHC (Abnova)

OS

Cy

7

Thirumurthi [23]

2014

China

BRC

NR

126

NR

IHC (CST)

OS

NR

8

Khongkow [24]

2013

China

BRC

I–III

118

NR

IHC (CST)

OS

Nu

8

  1. NR not report, M month, IHC immunohistochemistry, OC ovarian carcinomas, CRC colon cancer, NSCLC non-small cell lung cancer, GC gastric cancer, PDAC pancreatic ductal adenocarcinoma, HCC hepatocellular carcinoma, BRC breast cancer, OS osteosarcoma, Nu nucleus, Cy cytoplasm