Subgroups | OS | DFS | ||
---|---|---|---|---|
HR (95% CI) | I2 (P-value) | HR (95% CI) | I2 (P-value) | |
Location | ||||
 Nu | 0.86 (0.45–1.66) | 82.5% (P < 0.001) | 0.62 (0.26–0.91) | 88.2% (P < 0.001) |
 Cy | 0.30 (0.18–0.50) | 0.0% (P = 1.000) | – | – |
 NR | 0.65 (0.38–1.13) | 81.8% (P < 0.001) | 0.37 (0.14–0.97) | 76.5% (P = 0.014) |
Region | ||||
 China | 0.79 (0.51–1.23) | 78.0% (P < 0.001) | 0.80 (0.22–2.88) | 91.9% (P < 0.001) |
 Other | 0.44 (0.19–1.03) | 88.4% (P < 0.001) | 0.32 (0.19–0.54) | 41.8% (P = 0.180) |
Patients number | ||||
 ≥ 100 | 0.56 (0.36–0.88) | 80.7% (P < 0.001) | 0.48 (0.26–0.91) | 0.0% (P = 0.384) |
 < 100 | 0.80 (0.39–1.65) | 82.9% (P < 0.001) | 0.70 (0.18–2.78) | 85.7% (P = 0.001) |
NOS score | ||||
 > 7 | 0.54 (0.27–1.07) | 82.8% (P < 0.001) | 0.26 (0.14–0.48) | 28.3% (P = 0.237) |
 ≤ 7 | 0.74 (0.45–1.23) | 82.8% (P < 0.001) | 0.48 (0.26–0.91) | 87.9% (P < 0.001) |
Publication year | ||||
 ≥ 2018 | 0.77 (0.37–1.60) | 87.1% (P < 0.001) | 0.40 (0.17–0.94) | 88.5% (P < 0.001) |
 ≤ 2017 | 0.59 (0.37–0.94) | 78.3% (P < 0.001) | 0.48 (0.26–0.91) | 83.8% (P < 0.001) |