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Fig. 3 | Cancer Cell International

Fig. 3

From: HOXA7 promotes the metastasis of KRAS mutant colorectal cancer by regulating myeloid-derived suppressor cells

Fig. 3

HOXA7 promotes KRAS mutant CRC metastasis and increases the infiltration of MDSCs. A, B The infiltration of immune cells into CT26-control and CT26-HOXA7 tumors (n = 10 for each group) was analyzed by flow cytometry. C The expression of HOXA7 and infiltration of MDSCs and CD8+ T cells in the two groups were analyzed by IHC. D The correlation between HOXA7 expression and CD11b or CD8 expression in KRAS mutant CRC tissues. The upper P values represent the results of comparing the infiltration of CD11b+ cells in the HOXA7-negative group and HOXA7-positive group. The lower P values represent the results of comparing the infiltration of CD8+ T cells in the HOXA7-negative group and HOXA7-positive group. E IHC staining showing HOXA7, CD11b, and CD8 expression in KRAS mutant CRC and KRAS wild-type CRC tissues

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Cancer Cell International

ISSN: 1475-2867

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