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Fig. 7 | Cancer Cell International

Fig. 7

From: Pan-cancer analysis of oncogenic role of Programmed Cell Death 2 Like (PDCD2L) and validation in colorectal cancer

Fig. 7

Down-regulation of PDCD2L expression promotes apoptosis in CRC cells. A PDCD2L expression was downregulated in HT29cells transfected with 3 different PDCD2L siRNA sequences by qPCR. B and C transcription level and protein level of PDCD2L in HT29 and SW480 were significantly downregulated by si-PDCD2L-3 transfection, respectively. D–F PDCD2L knockdown significantly increased the total apoptosis rate of HT29 and SW480. G–J cell proliferation was assessed by CCK assay and EdU assay. K PDCD2L-related signaling pathways were determined by western blot. (** P < .01; **** P < .0001)

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Cancer Cell International

ISSN: 1475-2867

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