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Fig. 7 | Cancer Cell International

Fig. 7

From: Tumor-associated macrophage derived IL-6 enriches cancer stem cell population and promotes breast tumor progression via Stat-3 pathway

Fig. 7

TAM derived IL-6 induces CSC enrichment and breast tumor growth in breast cancer. Proposed working model showing the breast cancer mediated activation of macrophages leads to enhanced IL-6 production. Further, activated macrophages derived IL-6 regulates breast cancer stem cell enrichment and subsequent tumor progression through STAT-3 pathway

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