From: The importance of miRNA-630 in human diseases with an especial focus on cancers
Samples | Kaplan Meier | Multivariate Cox analysis | Refs. |
---|---|---|---|
33 renal cell carcinoma (RCC) tissues | – | Up-regulation of miR-630 was correlated with TNM stage class I | [36] |
92 RCC tissues | Up-regulation of miR-630 was correlated with the unfavorable prognosis of patients | Up-regulation of miR-630 was correlated with the grade, lymph node metastasis, and distant metastasis | [33] |
53 ovarian cancer (OC) tissues | – | High level of miR-630 was correlated with higher stages and lymph node metastasis | [12] |
114 tumor tissues of non-small cell lung cancer (NSCLC) | Low level of miR-630 and high level of BCL2 correlated with weak outcomes in the patients | The advanced stage of tumors was associated with low level of miR-630 | [34] |
42 pairs of hepatocellular carcinoma (HCC) tumors and ANCTs | There was a positive correlation between miR-630 expression and the patient’s prognosis | There was a positive correlation between miR-630 expression and advanced stage (II–III), micro and macro-vascular invasion | [14] |
97 HCC patient tissues | Low level of miR-630 was associated with the poor prognosis | There was a correlation between low levels of miR-630 with metastasis probability, incomplete encapsulation, advanced edmondson stage, advanced TNM stage, advanced BCLC stage, high tumor number, and vascular invasion possibility | [15] |
46 NSCLC tumor samples | Low level of miR-630 was correlated with a worse prognosis | Low level of miR-630 usually observed in advanced stages (II, III, and IV) | [37] |
Tumor tissue from 118 gastric cancer (GC) patients | Low level of miR-630 was associated with the poor prognosis | There was correlation between miR-630 expression with tumor size, lymph node metastasis, depth of invasion, and stage | [18] |
236 GC tumors (intestinal and diffuse type) | miR-630 up-regulation was associated with poor overall survival | miR-630 over-expression correlated with invasion, lymph node and distant metastasis, and TNM stage | [35] |
147 osteosarcoma tissues | Low level of miR-630 was associated with the worse prognosis | There was a correlation between low miR-630 expression with higher stage and distant metastasis | [29] |
Peripheral blood from 58 esophageal cancer patients | Low level of miR-630 was associated with poor prognosis | The levels of miR-630 were associated with disease course, stage, differentiation degree, and metastasis | [31] |
44 esophageal squamous cell carcinoma (ESCC) tumors | Low level of miR-630 was associated with the unfavorable prognosis | The levels of miR-630 were associated with tumor range, lymphatic metastasis, and stage | [32] |
116 pairs of bladder urothelial carcinoma and ANCTs, 42 normal tissue | High level of miR-630 was associated with the worse prognosis | There was a correlation between high miR-630 level with advanced TNM stage, higher grade and, lymph node metastasis | [38] |
206 colorectal cancer (CRC) | High miR-630 expression was associated with poor overall survival | High expression of miR-630 correlated with tumor invasion (T3+T4), lymph node metastasis, distant metastasis, and advanced TNM stage | [39] |