Table 1 Patient’s characteristics
From: Microbial and molecular differences according to the location of head and neck cancers
Variables | RNA (N = 519) | Variables | DNA (N = 172) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Oral (314) | Non-oral (205) | P-value | Oral (115) | Non-oral (57) | P-value | ||||||||
Age |  < 66 | 202 | (64%) | 154 | (75%) | 0.030* | Age |  < 66 | 80 | (70%) | 43 | (75%) | 0.476 |
 ≥ 66 | 111 | (35%) | 51 | (25%) |  ≥ 66 | 35 | (30%) | 14 | (25%) | ||||
NA | 1 | (0%) | – | – | NA | – | – | – | – | ||||
Gender | Female | 102 | (32%) | 34 | (17%) | 8.698E-05*** | Gender | Female | 41 | (36%) | – | – | 2.372E-06*** |
Male | 212 | (68%) | 171 | (83%) | Male | 74 | (64%) | 51 | (89%) | ||||
HPV status | positive | 32 | (10%) | 65 | (32%) | 1.623E-09*** | HPV status | Positive | 16 | (14%) | 31 | (54%) | 5.201E-08*** |
negative | 282 | (90%) | 140 | (68%) | Negative | 99 | (86%) | 26 | (46%) | ||||
NA | 1 | (0%) | – | – | NA | – | – | – | – | ||||
Clinical Stage | Stage I | 12 | (4%) | 8 | (4%) | 3.998E-03** 4.998E-04*** | Clinical stage | Stage I | 4 | (3%) | – | – | 1.100E-03** |
Stage II | 76 | (24%) | 22 | (11%) | Stage II | 29 | (25%) | 9 | (16%) | ||||
Stage III | 65 | (21%) | 40 | (20%) | Stage III | 29 | (25%) | 7 | (12%) | ||||
Stage IVA | 146 | (46%) | 118 | (58%) | Stage IVA | 53 | (46%) | 35 | (61%) | ||||
Stage IVB | 4 | (1%) | 7 | (3%) | Stage IVB | – | – | 4 | (7%) | ||||
Stage IVC | 3 | (1%) | 4 | (2%) | Stage IVC | – | – | 1 | (2%) | ||||
NA | 8 | (3%) | 6 | (3%) | NA | – | – | 1 | (2%) | ||||
Pathologic Stage | StageI | 21 | (7%) | 6 | (3%) | Pathologic stage | Stage I | 9 | (8%) | 2 | (4%) | 2.733E-05*** | |
Stage II | 54 | (17%) | 20 | (10%) | Stage II | 22 | (19%) | 4 | (7%) | ||||
Stage III | 56 | (18%) | 25 | (12%) | Stage III | 18 | (16%) | 8 | (14%) | ||||
Stage IVA | 154 | (49%) | 98 | (48%) | Stage IVA | 56 | (49%) | 19 | (33%) | ||||
Stage IVB | 7 | (2%) | 5 | (2%) | Stage IVB | 1 | (1%) | 2 | (4%) | ||||
Stage IVC | – | – | 1 | (0%) | Stage IVC | – | – | – | – | ||||
NA | 22 | (7%) | 50 | (24%) | NA | 9 | (8%) | 22 | (39%) | ||||
Race | American Indian or Alaska native | 1 | (0%) | 1 | (0%) | 0.029* | Race | American Indian or Alaska native | – | – | – | – | 0.379 |
Asian | 10 | (3%) | 1 | (0%) | Asian | 2 | (2%) | – | – | ||||
Black or African American | 22 | (7%) | 26 | (13%) | Black or African American | 6 | (5%) | 6 | (11%) | ||||
White | 270 | (86%) | 173 | (84%) | White | 105 | (91%) | 51 | (89%) | ||||
NA | 11 | (4%) | 4 | (2%) | NA | 2 | (2%) | – | – | ||||
Alcohol History | Yes | 202 | (64%) | 144 | (70%) | 0.393 | Alcohol history | Yes | 72 | (63%) | 48 | (84%) | 1.913E-03** |
NO | 105 | (33%) | 57 | (28%) | NO | 41 | (36%) | 7 | (12%) | ||||
NA | 7 | (2%) | 4 | (2%) | Â | NA | 2 | (2%) | 2 | (4%) | |||
Pack Years Smoked | 30 <  | 52 | (17%) | 37 | (18%) | 0.014* | Pack years smoked | 30 <  | 16 | (14%) | 12 | (21%) | 0.174 |
30≥ | 111 | (35%) | 95 | (46%) | 30 ≥  | 42 | (37%) | 25 | (44%) | ||||
NA | 151 | (48%) | 73 | (36%) | NA | 57 | (50%) | 20 | (35%) | ||||